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Functional Analyses of Transcription Factor Binding Sites that Differ between Present-Day and Archaic Humans

We analyze 25 previously identified transcription factor binding sites that carry DNA sequence changes that are present in all or nearly all present-day humans, yet occur in the ancestral state in Neandertals and Denisovans, the closest evolutionary relatives of humans. When the ancestral and derive...

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Detalles Bibliográficos
Autores principales: Weyer, Sven, Pääbo, Svante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866544/
https://www.ncbi.nlm.nih.gov/pubmed/26454764
http://dx.doi.org/10.1093/molbev/msv215