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Enantioselective CuH-Catalyzed Reductive Coupling of Aryl Alkenes and Activated Carboxylic Acids

[Image: see text] A new method for the enantioselective reductive coupling of aryl alkenes with activated carboxylic acid derivatives via copper hydride catalysis is described. Dual catalytic cycles are proposed, with a relatively fast enantioselective hydroacylation cycle followed by a slower diast...

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Detalles Bibliográficos
Autores principales: Bandar, Jeffrey S., Ascic, Erhad, Buchwald, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866599/
https://www.ncbi.nlm.nih.gov/pubmed/27121395
http://dx.doi.org/10.1021/jacs.6b03086