Structural basis for the blockade of MATE multidrug efflux pumps

Multidrug and toxic compound extrusion (MATE) transporters underpin multidrug resistance by using the H(+) or Na(+) electrochemical gradient to extrude different drugs across cell membranes. MATE transporters can be further parsed into the DinF, NorM and eukaryotic subfamilies based on their amino-a...

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Detalles Bibliográficos
Autores principales: Radchenko, Martha, Symersky, Jindrich, Nie, Rongxin, Lu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866600/
https://www.ncbi.nlm.nih.gov/pubmed/26246409
http://dx.doi.org/10.1038/ncomms8995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866600/
https://www.ncbi.nlm.nih.gov/pubmed/26246409
http://dx.doi.org/10.1038/ncomms8995

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