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Molecular Dynamics of "Fuzzy" Transcriptional Activator-Coactivator Interactions

Transcriptional activation domains (ADs) are generally thought to be intrinsically unstructured, but capable of adopting limited secondary structure upon interaction with a coactivator surface. The indeterminate nature of this interface made it hitherto difficult to study structure/function relation...

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Detalles Bibliográficos
Autores principales: Scholes, Natalie S., Weinzierl, Robert O. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866707/
https://www.ncbi.nlm.nih.gov/pubmed/27175900
http://dx.doi.org/10.1371/journal.pcbi.1004935