A Method for Checking Genomic Integrity in Cultured Cell Lines from SNP Genotyping Data

Genomic screening for chromosomal abnormalities is an important part of quality control when establishing and maintaining stem cell lines. We present a new method for sensitive detection of copy number alterations, aneuploidy, and contamination in cell lines using genome-wide SNP genotyping data. In...

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Detalles Bibliográficos
Autores principales: Danecek, Petr, McCarthy, Shane A., Durbin, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866717/
https://www.ncbi.nlm.nih.gov/pubmed/27176002
http://dx.doi.org/10.1371/journal.pone.0155014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866717/
https://www.ncbi.nlm.nih.gov/pubmed/27176002
http://dx.doi.org/10.1371/journal.pone.0155014

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