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A Method for Checking Genomic Integrity in Cultured Cell Lines from SNP Genotyping Data
Genomic screening for chromosomal abnormalities is an important part of quality control when establishing and maintaining stem cell lines. We present a new method for sensitive detection of copy number alterations, aneuploidy, and contamination in cell lines using genome-wide SNP genotyping data. In...
Autores principales: | Danecek, Petr, McCarthy, Shane A., Durbin, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866717/ https://www.ncbi.nlm.nih.gov/pubmed/27176002 http://dx.doi.org/10.1371/journal.pone.0155014 |
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