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Benchmarking Inverse Statistical Approaches for Protein Structure and Design with Exactly Solvable Models
Inverse statistical approaches to determine protein structure and function from Multiple Sequence Alignments (MSA) are emerging as powerful tools in computational biology. However the underlying assumptions of the relationship between the inferred effective Potts Hamiltonian and real protein structu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866778/ https://www.ncbi.nlm.nih.gov/pubmed/27177270 http://dx.doi.org/10.1371/journal.pcbi.1004889 |