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Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels

G protein gated inward rectifier K(+) (GIRK) channels open and thereby silence cellular electrical activity when inhibitory G protein coupled receptors (GPCRs) are stimulated. Here we describe an assay to measure neuronal GIRK2 activity as a function of membrane-anchored G protein concentration. Usi...

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Detalles Bibliográficos
Autores principales:	Wang, Weiwei, Touhara, Kouki K, Weir, Keiko, Bean, Bruce P, MacKinnon, Roderick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866826/ https://www.ncbi.nlm.nih.gov/pubmed/27074662 http://dx.doi.org/10.7554/eLife.15751

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