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Docosahexenoic acid treatment ameliorates cartilage degeneration via a p38 MAPK-dependent mechanism

Osteoarthritis (OA) is a common chronic inflammatory disease, characterized by cartilage degradation. The aberrant expression of matrix metalloproteinase-13 (MMP-13) plays a vital role in the pathogenesis of OA. The anti-inflammatory property of docosahexenoic acid (DHA) was previously revealed and...

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Detalles Bibliográficos
Autores principales: WANG, ZHENZHONG, GUO, AI, MA, LIFENG, YU, HAOMIAO, ZHANG, LIANG, MENG, HAI, CUI, YINPENG, YU, FEI, YANG, BO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866951/
https://www.ncbi.nlm.nih.gov/pubmed/27082436
http://dx.doi.org/10.3892/ijmm.2016.2567