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Berberine Inhibition of Fibrogenesis in a Rat Model of Liver Fibrosis and in Hepatic Stellate Cells

Aim. To examine the effect of berberine (BBR) on liver fibrosis and its possible mechanisms through direct effects on hepatic stellate cells (HSC). Methods. The antifibrotic effect of BBR was determined in a rat model of bile duct ligation- (BDL-) induced liver fibrosis. Multiple cellular and molecu...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Xu, Qihe, Tan, Hor Yue, Hong, Ming, Li, Sha, Yuen, Man-Fung, Feng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867075/
https://www.ncbi.nlm.nih.gov/pubmed/27239214
http://dx.doi.org/10.1155/2016/8762345