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A Novel Hydrodynamic Injection Mouse Model of HBV Genotype C for the Study of HBV Biology and the Anti-Viral Activity of Lamivudine

BACKGROUND: Absence of an immunocompetent mouse model of persistent hepatitis B virus (HBV) infection has hindered the research of HBV infection and the development of antiviral medications. OBJECTIVES: In the present study, we aimed to develop a novel HBV genotype C mouse model by hydrodynamic inje...

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Detalles Bibliográficos
Autores principales: Li, Xiumei, Liu, Guangze, Chen, Meijuan, Yang, Yang, Xie, Yong, Kong, Xiangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867405/
https://www.ncbi.nlm.nih.gov/pubmed/27195013
http://dx.doi.org/10.5812/hepatmon.34420