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Low-dose lipopolysaccharide (LPS) inhibits aggressive and augments depressive behaviours in a chronic mild stress model in mice

BACKGROUND: Aggression, hyperactivity, impulsivity, helplessness and anhedonia are all signs of depressive-like disorders in humans and are often reported to be present in animal models of depression induced by stress or by inflammatory challenges. However, chronic mild stress (CMS) and clinically s...

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Detalles Bibliográficos
Autores principales: Couch, Yvonne, Trofimov, Alexander, Markova, Natalyia, Nikolenko, Vladimir, Steinbusch, Harry W., Chekhonin, Vladimir, Schroeter, Careen, Lesch, Klaus-Peter, Anthony, Daniel C., Strekalova, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867526/
https://www.ncbi.nlm.nih.gov/pubmed/27184538
http://dx.doi.org/10.1186/s12974-016-0572-0