LASP1-S100A11 axis promotes colorectal cancer aggressiveness by modulating TGFβ/Smad signaling

LIM and SH3 protein 1(LASP1) can promote colorectal cancer (CRC) progression and metastasis, but the mechanism remains unclear. Here, we show that LASP1 interacts with S100 calcium binding protein A11(S100A11) and enhances its expression in CRC. LASP1-S100A11 axis is essential for TGFβ-mediated epit...

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Detalles Bibliográficos
Autores principales: Niu, Ya, Shao, Ziyun, Wang, Hui, Yang, Jiaqi, Zhang, Feifei, Luo, Yuhao, Xu, Lijun, Ding, Yanqing, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867635/
https://www.ncbi.nlm.nih.gov/pubmed/27181092
http://dx.doi.org/10.1038/srep26112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867635/
https://www.ncbi.nlm.nih.gov/pubmed/27181092
http://dx.doi.org/10.1038/srep26112

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