Potentiation of Glucose-stimulated Insulin Secretion by the GPR40–PLC–TRPC Pathway in Pancreatic β-Cells

G protein-coupled receptors (GPCRs) are expressed in pancreatic beta-cells. G protein-coupled receptor 40 (GPR40) contributes to medium- or long-chain fatty acid-induced amplification of glucose-stimulated insulin secretion (GSIS), and GPR40 agonists are promising therapeutic targets in type 2 diabe...

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Detalles Bibliográficos
Autores principales: Yamada, Hodaka, Yoshida, Masashi, Ito, Kiyonori, Dezaki, Katsuya, Yada, Toshihiko, Ishikawa, San-e, Kakei, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867641/
https://www.ncbi.nlm.nih.gov/pubmed/27180622
http://dx.doi.org/10.1038/srep25912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867641/
https://www.ncbi.nlm.nih.gov/pubmed/27180622
http://dx.doi.org/10.1038/srep25912

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