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Rapid, scalable, and low-cost purification of recombinant adeno-associated virus produced by baculovirus expression vector system
Recombinant adeno-associated viruses (rAAV) are largely used for gene transfer in research, preclinical developments, and clinical trials. Their broad in vivo biodistribution and long-term efficacy in postmitotic tissues make them good candidates for numerous gene transfer applications. Upstream pro...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867670/ https://www.ncbi.nlm.nih.gov/pubmed/27226971 http://dx.doi.org/10.1038/mtm.2016.35 |