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Screening of cytoprotectors against methotrexate-induced cytogenotoxicity from bioactive phytochemicals
As a well known anti-neoplastic drug, the cytogenotoxicity of methotrexate (MTX) has received more attention in recent years. To develop a new cytoprotector to reduce the risk of second cancers caused by methotrexate, an umu test combined with a micronucleus assay was employed to estimate the cytopr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867711/ https://www.ncbi.nlm.nih.gov/pubmed/27190706 http://dx.doi.org/10.7717/peerj.1983 |