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In-vivo evidence that high mobility group box 1 exerts deleterious effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model and Parkinson's disease which can be attenuated by glycyrrhizin

High-mobility group box 1 (HMGB1) is a nuclear and cytosolic protein that is released during tissue damage from immune and non-immune cells — including microglia and neurons. HMGB1 can contribute to progression of numerous chronic inflammatory and autoimmune diseases which is mediated in part by int...

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Detalles Bibliográficos
Autores principales: Santoro, Matteo, Maetzler, Walter, Stathakos, Petros, Martin, Heather L., Hobert, Markus A., Rattay, Tim W., Gasser, Thomas, Forrester, John V., Berg, Daniela, Tracey, Kevin J., Riedel, Gernot, Teismann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867789/
https://www.ncbi.nlm.nih.gov/pubmed/26921471
http://dx.doi.org/10.1016/j.nbd.2016.02.018