Large-Effect Beneficial Synonymous Mutations Mediate Rapid and Parallel Adaptation in a Bacterium

Contrary to previous understanding, recent evidence indicates that synonymous codon changes may sometimes face strong selection. However, it remains difficult to generalize the nature, strength, and mechanism(s) of such selection. Previously, we showed that synonymous variants of a key enzyme-coding...

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Detalles Bibliográficos
Autores principales: Agashe, Deepa, Sane, Mrudula, Phalnikar, Kruttika, Diwan, Gaurav D., Habibullah, Alefiyah, Martinez-Gomez, Norma Cecilia, Sahasrabuddhe, Vinaya, Polachek, William, Wang, Jue, Chubiz, Lon M., Marx, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868122/
https://www.ncbi.nlm.nih.gov/pubmed/26908584
http://dx.doi.org/10.1093/molbev/msw035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868122/
https://www.ncbi.nlm.nih.gov/pubmed/26908584
http://dx.doi.org/10.1093/molbev/msw035

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