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Large-Effect Beneficial Synonymous Mutations Mediate Rapid and Parallel Adaptation in a Bacterium
Contrary to previous understanding, recent evidence indicates that synonymous codon changes may sometimes face strong selection. However, it remains difficult to generalize the nature, strength, and mechanism(s) of such selection. Previously, we showed that synonymous variants of a key enzyme-coding...
Autores principales: | Agashe, Deepa, Sane, Mrudula, Phalnikar, Kruttika, Diwan, Gaurav D., Habibullah, Alefiyah, Martinez-Gomez, Norma Cecilia, Sahasrabuddhe, Vinaya, Polachek, William, Wang, Jue, Chubiz, Lon M., Marx, Christopher J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868122/ https://www.ncbi.nlm.nih.gov/pubmed/26908584 http://dx.doi.org/10.1093/molbev/msw035 |
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