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Genomic African and Native American Ancestry and Chagas Disease: The Bambui (Brazil) Epigen Cohort Study of Aging

BACKGROUND: The influence of genetic ancestry on Trypanosoma cruzi infection and Chagas disease outcomes is unknown. METHODOLOGY/PRINCIPAL FINDINGS: We used 370,539 Single Nucleotide Polymorphisms (SNPs) to examine the association between individual proportions of African, European and Native Americ...

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Detalles Bibliográficos
Autores principales: Lima-Costa, M. Fernanda, Macinko, James, Mambrini, Juliana Vaz de Mello, Peixoto, Sérgio Viana, Pereira, Alexandre Costa, Tarazona-Santos, Eduardo, Ribeiro, Antonio Luiz Pinho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868305/
https://www.ncbi.nlm.nih.gov/pubmed/27182885
http://dx.doi.org/10.1371/journal.pntd.0004724