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Characterization of Novel Hepatitis B Virus PreS/S-Gene Mutations in a Patient with Occult Hepatitis B Virus Infection

OBJECTIVE: The impact of hepatitis B virus (HBV) preS/S-gene mutations on occult HBV infection (OBI) is not fully understood. This study characterized multiple novel HBV preS/S-gene mutants obtained from an OBI patient. METHODS: PreS/S-gene mutants were analyzed by clonal sequencing. Viral replicati...

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Detalles Bibliográficos
Autores principales: Chen, Jianhong, Liu, Yan, Zhao, Jun, Xu, Zhihui, Chen, Rongjuan, Si, Lanlan, Lu, Shanshan, Li, Xiaodong, Wang, Shuai, Zhang, Kai, Li, Jin, Han, Juqiang, Xu, Dongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868315/
https://www.ncbi.nlm.nih.gov/pubmed/27182775
http://dx.doi.org/10.1371/journal.pone.0155654