Cathepsin B-Deficient Mice Resolve Leishmania major Inflammation Faster in a T Cell-Dependent Manner

A critical role for intracellular TLR9 has been described in recognition and host resistance to Leishmania parasites. As TLR9 requires endolysosomal proteolytic cleavage to achieve signaling functionality, we investigated the contribution of different proteases like asparagine endopeptidase (AEP) or...

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Detalles Bibliográficos
Autores principales: Rasid, Orhan, Mériaux, Véronique, Khan, Erin M., Borde, Chloé, Ciulean, Ioana S., Fitting, Catherine, Manoury, Bénédicte, Cavaillon, Jean-Marc, Doyen, Noëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868322/
https://www.ncbi.nlm.nih.gov/pubmed/27182703
http://dx.doi.org/10.1371/journal.pntd.0004716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868322/
https://www.ncbi.nlm.nih.gov/pubmed/27182703
http://dx.doi.org/10.1371/journal.pntd.0004716

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