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Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain

Communication between pre- and postsynaptic cells promotes the initial organization of synaptic specializations, but subsequent synaptic stabilization requires transcriptional regulation. Here we show that fibroblast growth factor 22 (FGF22), a target-derived presynaptic organizer in the mouse hippo...

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Detalles Bibliográficos
Autores principales: Terauchi, Akiko, Johnson-Venkatesh, Erin M, Bullock, Brenna, Lehtinen, Maria K, Umemori, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868541/
https://www.ncbi.nlm.nih.gov/pubmed/27083047
http://dx.doi.org/10.7554/eLife.12151