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Relationship between triterpenoid anticancer drug resistance, autophagy, and caspase-1 in adult T-cell leukemia

We previously reported that the inflammasome inhibitor cucurbitacin D (CuD) induces apoptosis in human leukemia cell lines. Here, we investigated the effects of CuD and a B-cell lymphoma extra-large (Bcl-xL) inhibitor on autophagy in peripheral blood lymphocytes (PBL) isolated from adult T-cell leuk...

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Detalles Bibliográficos
Autores principales: Nakanishi, Tsukasa, Song, Yuan, He, Cuiying, Wang, Duo, Morita, Kentaro, Tsukada, Junichi, Kanazawa, Tamotsu, Yoshida, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868592/
https://www.ncbi.nlm.nih.gov/pubmed/27190722
http://dx.doi.org/10.7717/peerj.2026