XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence

X-linked inhibitor of apoptosis (XIAP)-associated factor 1 (XAF1) is well known as an antagonist of XIAP-mediated caspase inhibition. Although XAF1 serves as a tumor-suppressor gene, the role of XAF1 in cellular senescence remains unclear. We found that XAF1 expression was increased by genotoxic age...

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Detalles Bibliográficos
Autores principales: Heo, Jong-Ik, Kim, Wonwoo, Choi, Kyu Jin, Bae, Sangwoo, Jeong, Jae-Hoon, Kim, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868675/
https://www.ncbi.nlm.nih.gov/pubmed/26802028
http://dx.doi.org/10.18632/oncotarget.6962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868675/
https://www.ncbi.nlm.nih.gov/pubmed/26802028
http://dx.doi.org/10.18632/oncotarget.6962

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