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Bcl-2 family proteins as regulators of cancer cell invasion and metastasis: a review focusing on mitochondrial respiration and reactive oxygen species
Although Bcl-2 family proteins were originally identified as key regulators of apoptosis, an impressive body of evidence has shown that pro-survival members of the Bcl-2 family, including Bcl-2, Bcl-X(L), and Bcl-w, can also promote cell migration, invasion, and cancer metastasis. Interestingly, cel...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Impact Journals LLC
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868680/ https://www.ncbi.nlm.nih.gov/pubmed/26621844 http://dx.doi.org/10.18632/oncotarget.6405 |