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A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis
A recently conducted chemical genetic screen for pharmaceuticals that can extend longevity of the yeast Saccharomyces cerevisiae has identified lithocholic acid as a potent anti-aging molecule. It was found that this hydrophobic bile acid is also a selective anti-tumor chemical compound; it kills di...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868681/ https://www.ncbi.nlm.nih.gov/pubmed/26636650 http://dx.doi.org/10.18632/oncotarget.6440 |