Expression of the FGFR2 mesenchymal splicing variant in epithelial cells drives epithelial-mesenchymal transition

The FGFRs are receptor tyrosine kinases expressed by tissue-specific alternative splicing in epithelial IIIb or mesenchymal IIIc isoforms. Deregulation of FGF/FGFR signaling unbalances the epithelial-stromal homeostasis and may lead to cancer development. In the epithelial-context, while FGFR2b/KGFR...

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Detalles Bibliográficos
Autores principales: Ranieri, Danilo, Rosato, Benedetta, Nanni, Monica, Magenta, Alessandra, Belleudi, Francesca, Torrisi, Maria Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868697/
https://www.ncbi.nlm.nih.gov/pubmed/26713601
http://dx.doi.org/10.18632/oncotarget.6706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868697/
https://www.ncbi.nlm.nih.gov/pubmed/26713601
http://dx.doi.org/10.18632/oncotarget.6706

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