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HER-3 targeting alters the dimerization pattern of ErbB protein family members in breast carcinomas

Breast carcinogenesis is a multi-step process in which membrane receptor tyrosine kinases are crucial participants. Lots of research has been done on epidermal growth factor receptor (EGFR) and HER-2 with important clinical results. However, breast cancer patients present intrinsic or acquired resis...

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Detalles Bibliográficos
Autores principales: Karamouzis, Michalis V., Dalagiorgou, Georgia, Georgopoulou, Urania, Nonni, Afroditi, Kontos, Michalis, Papavassiliou, Athanasios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868707/
https://www.ncbi.nlm.nih.gov/pubmed/26716646
http://dx.doi.org/10.18632/oncotarget.6762