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Combating autophagy is a strategy to increase cytotoxic effects of novel ALK inhibitor entrectinib in neuroblastoma cells

Neuroblastoma (NB) is a threatening childhood malignancy. Its prognosis is affected by several morphological, and biological characteristics, including the constitutive expression of ALK tyrosine kinase. In this study we examined the therapeutic potential of a novel ALK inhibitor, entrectinib, in ob...

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Detalles Bibliográficos
Autores principales: Aveic, Sanja, Pantile, Marcella, Seydel, Anke, Esposito, Maria Rosaria, Zanon, Carlo, Li, Gary, Tonini, Gian Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868711/
https://www.ncbi.nlm.nih.gov/pubmed/26735175
http://dx.doi.org/10.18632/oncotarget.6778