A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma

Background: Evidence suggests that Src homologous protein phosphotyrosyl phosphatase 2 (SHP2) mutations promote cancer development in several solid tumours. In this study, we focused on the in vivo and in vitro effects of an SHP2 mutation on the breast cancer phenotype to determine whether this muta...

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Detalles Bibliográficos
Autores principales: Hu, Zhongqian, Wang, Xinyi, Fang, Haoshu, Liu, Yakun, Chen, Danlei, Zhang, Qian, Liu, Xia, Wei, Daoyan, Qu, Chengkui, Wang, Siying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868712/
https://www.ncbi.nlm.nih.gov/pubmed/26673822
http://dx.doi.org/10.18632/oncotarget.6561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868712/
https://www.ncbi.nlm.nih.gov/pubmed/26673822
http://dx.doi.org/10.18632/oncotarget.6561

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