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Down-regulation of the zinc-finger homeobox protein TSHZ2 releases GLI1 from the nuclear repressor complex to restore its transcriptional activity during mammary tumorigenesis

Although breast cancer is one of the most common malignancies, the molecular mechanisms underlying its development and progression are not fully understood. To identify key molecules involved, we screened publicly available microarray datasets for genes differentially expressed between breast cancer...

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Detalles Bibliográficos
Autores principales: Riku, Miho, Inaguma, Shingo, Ito, Hideaki, Tsunoda, Takumi, Ikeda, Hiroshi, Kasai, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868714/
https://www.ncbi.nlm.nih.gov/pubmed/26744317
http://dx.doi.org/10.18632/oncotarget.6788