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Wogonin inhibits multiple myeloma-stimulated angiogenesis via c-Myc/VHL/HIF-1α signaling axis

Angiogenesis is associated with the progression of multiple myeloma (MM). Wogonin is an active mono-flavonoid with remarkable antitumor activity. However, its impact on MM-stimulated angiogenesis remains largely unknown. Here, we demonstrated that wogonin decreased expression and secretion of pro-an...

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Detalles Bibliográficos
Autores principales: Fu, Rong, Chen, Yan, Wang, Xiao-Ping, An, Teng, Tao, Lei, Zhou, Yu-Xin, Huang, Yu-Jie, Chen, Bao-An, Li, Zhi-Yu, You, Qi-Dong, Guo, Qing-Long, Wu, Zhao-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868716/
https://www.ncbi.nlm.nih.gov/pubmed/26735336
http://dx.doi.org/10.18632/oncotarget.6796