Cargando…

Notch and Wnt/β-catenin signaling pathway play important roles in activating liver cancer stem cells

Human hepatocellular carcinoma (HCC) is driven and maintained by liver cancer stem cells (LCSCs) that display stem cell properties. These LCSCs are promoted by the intersecting of Notch and Wnt/β-Catenin signaling pathways. In this study, we demonstrate that LCSCs with markers CD90, CD24, CD13, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ronghua, Sun, Qian, Wang, Peng, Liu, Man, Xiong, Si, Luo, Jing, Huang, Hai, Du, Qiang, Geller, David A., Cheng, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868719/
https://www.ncbi.nlm.nih.gov/pubmed/26735577
http://dx.doi.org/10.18632/oncotarget.6805