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Notch and Wnt/β-catenin signaling pathway play important roles in activating liver cancer stem cells
Human hepatocellular carcinoma (HCC) is driven and maintained by liver cancer stem cells (LCSCs) that display stem cell properties. These LCSCs are promoted by the intersecting of Notch and Wnt/β-Catenin signaling pathways. In this study, we demonstrate that LCSCs with markers CD90, CD24, CD13, and...
Autores principales: | Wang, Ronghua, Sun, Qian, Wang, Peng, Liu, Man, Xiong, Si, Luo, Jing, Huang, Hai, Du, Qiang, Geller, David A., Cheng, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868719/ https://www.ncbi.nlm.nih.gov/pubmed/26735577 http://dx.doi.org/10.18632/oncotarget.6805 |
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