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Induction of autophagy promotes the growth of early preneoplastic rat liver nodules

Although inhibition of autophagy has been implicated in the onset and progression of cancer cells, it is still unclear whether its dysregulation at early stages of tumorigenesis plays an oncogenic or a tumor suppressor role. To address this question, we employed the Resistant-Hepatocyte rat model to...

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Detalles Bibliográficos
Autores principales: Kowalik, Marta Anna, Perra, Andrea, Ledda-Columbano, Giovanna Maria, Ippolito, Giuseppe, Piacentini, Mauro, Columbano, Amedeo, Falasca, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868721/
https://www.ncbi.nlm.nih.gov/pubmed/26735341
http://dx.doi.org/10.18632/oncotarget.6810