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RPS7 inhibits colorectal cancer growth via decreasing HIF-1α-mediated glycolysis

Ribosomal protein S7 (RPS7) acts as a tumor suppressor in primary tumorigenesis but its role in cancer metabolism remains unclear. In this study, we demonstrate that RPS7 inhibits the colorectal cancer (CRC) cell glycolysis by suppressing the expression of hypoxia-inducible transcription factor-1α (...

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Detalles Bibliográficos
Autores principales: Zhang, Wen, Tong, Duo, Liu, Fei, Li, Dawei, Li, Jiajia, Cheng, Xi, Wang, Ziliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868722/
https://www.ncbi.nlm.nih.gov/pubmed/26735579
http://dx.doi.org/10.18632/oncotarget.6807