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Gastro-duodenal fluid induced nuclear factor-κappaB activation and early pre-malignant alterations in murine hypopharyngeal mucosa

We recently described the role of gastro-duodenal fluids (GDFs) in generating changes consistent with hypopharyngeal neoplasia through activation of NF-κB pathway, using an in vitro model of human hypopharyngeal normal keratinocytes. Here, we further provide evidence that gastro-duodenal reflux is a...

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Detalles Bibliográficos
Autores principales: Vageli, Dimitra P., Prasad, Manju L., Sasaki, Clarence T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868729/
https://www.ncbi.nlm.nih.gov/pubmed/26745676
http://dx.doi.org/10.18632/oncotarget.6824