MiR-let-7a inhibits cell proliferation, migration, and invasion by down-regulating PKM2 in gastric cancer

In contrast to normal differentiated cells that depend on aerobicoxidation for energy production, cancer cells use aerobic glycolysis as the main source (Warburg's effect). The M2 splice isoform of pyruvate kinase (PKM2) is the key regulator for the aerobic glycolysis, high expression of PKM2 c...

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Detalles Bibliográficos
Autores principales: Tang, Ran, Yang, Chao, Ma, Xiang, Wang, Younan, Luo, Dakui, Huang, Chi, Xu, Zekuan, Liu, Ping, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868734/
https://www.ncbi.nlm.nih.gov/pubmed/26745603
http://dx.doi.org/10.18632/oncotarget.6821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868734/
https://www.ncbi.nlm.nih.gov/pubmed/26745603
http://dx.doi.org/10.18632/oncotarget.6821

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