Lanatoside C suppressed colorectal cancer cell growth by inducing mitochondrial dysfunction and increased radiation sensitivity by impairing DNA damage repair

Cardiac glycosides are clinically used for cardiac arrhythmias. In this study, we investigated the mechanism responsible for anti-cancer and radiosensitizing effects of lanatoside C in colorectal cancer cells. Lanatoside C-treated cells showed classic patterns of autophagy, which may have been cause...

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Detalles Bibliográficos
Autores principales: Kang, Mi Ae, Kim, Mi-Sook, Kim, Wonwoo, Um, Jee-Hyun, Shin, Young-Joo, Song, Jie-Young, Jeong, Jae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868741/
https://www.ncbi.nlm.nih.gov/pubmed/26756216
http://dx.doi.org/10.18632/oncotarget.6832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868741/
https://www.ncbi.nlm.nih.gov/pubmed/26756216
http://dx.doi.org/10.18632/oncotarget.6832

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