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A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers

Collagen structure has been shown to influence tumor cell invasion, metastasis and clinical outcome in breast cancer. However, it remains unclear how it affects other solid cancers. Here we utilized multi-photon laser scanning microscopy and Second Harmonic Generation to identify alterations to coll...

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Detalles Bibliográficos
Autores principales: Hanley, Christopher J., Noble, Fergus, Ward, Matthew, Bullock, Marc, Drifka, Cole, Mellone, Massimiliano, Manousopoulou, Antigoni, Johnston, Harvey E., Hayden, Annette, Thirdborough, Steve, Liu, Yuming, Smith, David M., Mellows, Toby, Kao, W. John, Garbis, Spiros D., Mirnezami, Alex, Underwood, Tim J., Eliceiri, Kevin W., Thomas, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868747/
https://www.ncbi.nlm.nih.gov/pubmed/26716418
http://dx.doi.org/10.18632/oncotarget.6740