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Mutations in PI3K/AKT pathway genes and amplifications of PIK3CA are associated with patterns of recurrence in gastric cancers

Mutations in genes involved in the PI3K/AKT pathway and amplifications of the PIK3CA gene in gastric cancer and their associations with clinicopathological characteristics and EBV infection were analyzed in this study. A total of 431 patients with gastric adenocarcinomas were enrolled, and 39 mutati...

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Detalles Bibliográficos
Autores principales: Fang, Wen-Liang, Huang, Kuo-Hung, Lan, Yuan-Tzu, Lin, Chien-Hsing, Chang, Shih-Ching, Chen, Ming-Huang, Chao, Yee, Lin, Wen-Chang, Lo, Su-Shun, Li, Anna Fen-Yau, Wu, Chew-Wun, Chiou, Shih-Hwa, Shyr, Yi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868750/
https://www.ncbi.nlm.nih.gov/pubmed/26701847
http://dx.doi.org/10.18632/oncotarget.6641