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Fast clearance of lipid droplets through MAP1S-activated autophagy suppresses clear cell renal cell carcinomas and promotes patient survival

Clear cell renal cell carcinoma (ccRCC) is composed of cells whose cytoplasm filled with lipid droplets, subcellular organelles coated with adipocyte differentiation-related protein (ADFP) for the storage of triacylglycerol converted from excess free fatty acids. Mammalian cells primarily use the au...

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Detalles Bibliográficos
Autores principales: Xu, Guibin, Jiang, Yaodong, Xiao, Yuansong, Liu, Xian-De, Yue, Fei, Li, Wenjiao, Li, Xun, He, Yongzhong, Jiang, Xianhan, Huang, Hai, Chen, Qi, Jonasch, Eric, Liu, Leyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868754/
https://www.ncbi.nlm.nih.gov/pubmed/26701856
http://dx.doi.org/10.18632/oncotarget.6669