Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation

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Oncogenic mutations regulate signaling within both tumor cells and adjacent stromal cells. Here, we show that oncogenic KRAS (KRAS(G12D)) also regulates tumor cell signaling via stromal cells. By combining cell-specific proteome labeling with multivariate phosphoproteomics, we analyzed heterocellula...

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Detalles Bibliográficos
Autores principales: Tape, Christopher J., Ling, Stephanie, Dimitriadi, Maria, McMahon, Kelly M., Worboys, Jonathan D., Leong, Hui Sun, Norrie, Ida C., Miller, Crispin J., Poulogiannis, George, Lauffenburger, Douglas A., Jørgensen, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868820/
https://www.ncbi.nlm.nih.gov/pubmed/27087446
http://dx.doi.org/10.1016/j.cell.2016.03.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868820/
https://www.ncbi.nlm.nih.gov/pubmed/27087446
http://dx.doi.org/10.1016/j.cell.2016.03.029

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