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Mycobacterium tuberculosis Co-operonic PE32/PPE65 Proteins Alter Host Immune Responses by Hampering Th1 Response

PE/PPE genes, present in cluster with ESAT-6 like genes, are suspected to have a role in antigenic variation and virulence of Mycobacterium tuberculosis. Their roles in immune evasion and immune modulation of host are also well documented. We present evidence that PE32/PPE65 present within the RD8 r...

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Detalles Bibliográficos
Autores principales: Khubaib, Mohd, Sheikh, Javaid A., Pandey, Saurabh, Srikanth, Battu, Bhuwan, Manish, Khan, Nooruddin, Hasnain, Seyed E., Ehtesham, Nasreen Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868851/
https://www.ncbi.nlm.nih.gov/pubmed/27242739
http://dx.doi.org/10.3389/fmicb.2016.00719