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Evaluation of Multiple Immunoassay Technology Platforms to Select the Anti-Drug Antibody Assay Exhibiting the Most Appropriate Drug and Target Tolerance

The aim of this study was, at the assay development stage and thus with an appropriate degree of rigor, to select the most appropriate technology platform and sample pretreatment procedure for a clinical ADA assay. Thus, ELISA, MSD, Gyrolab, and AlphaLISA immunoassay platforms were evaluated in asso...

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Detalles Bibliográficos
Autores principales: Collet-Brose, Justine, Couble, Pierre-Jean, Deehan, Maureen R., Nelson, Robert J., Ferlin, Walter G., Lory, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868908/
https://www.ncbi.nlm.nih.gov/pubmed/27243038
http://dx.doi.org/10.1155/2016/5069678