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KLF4 transcriptionally activates non-canonical WNT5A to control epithelial stratification

Epithelial differentiation and stratification are essential for normal homeostasis, and disruption of these processes leads to both injury and cancer. The zinc-finger transciption factor KLF4 is a key driver of epithelial differentiation, yet the mechanisms and targets by which KLF4 controls differe...

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Detalles Bibliográficos
Autores principales: Tetreault, Marie-Pier, Weinblatt, Daniel, Shaverdashvili, Khvaramze, Yang, Yizeng, Katz, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869036/
https://www.ncbi.nlm.nih.gov/pubmed/27184424
http://dx.doi.org/10.1038/srep26130