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KLF4 transcriptionally activates non-canonical WNT5A to control epithelial stratification
Epithelial differentiation and stratification are essential for normal homeostasis, and disruption of these processes leads to both injury and cancer. The zinc-finger transciption factor KLF4 is a key driver of epithelial differentiation, yet the mechanisms and targets by which KLF4 controls differe...
Autores principales: | Tetreault, Marie-Pier, Weinblatt, Daniel, Shaverdashvili, Khvaramze, Yang, Yizeng, Katz, Jonathan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869036/ https://www.ncbi.nlm.nih.gov/pubmed/27184424 http://dx.doi.org/10.1038/srep26130 |
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