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CP-25, a novel compound, protects against autoimmune arthritis by modulating immune mediators of inflammation and bone damage

Paeoniflorin-6′-O-benzene sulfonate (code: CP-25), a novel ester derivative of paeoniflorin (Pae), was evaluated in rats with adjuvant-induced arthritis (AA) to study its potential anti-arthritic activity. AA rats were treated with CP-25 (25, 50, or 100 mg/kg) from days 17 to 29 after immunization....

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Detalles Bibliográficos
Autores principales: Chang, Yan, Jia, Xiaoyi, Wei, Fang, Wang, Chun, Sun, Xiaojing, Xu, Shu, Yang, Xuezhi, Zhao, Yingjie, Chen, Jingyu, Wu, Huaxun, Zhang, Lingling, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869037/
https://www.ncbi.nlm.nih.gov/pubmed/27184722
http://dx.doi.org/10.1038/srep26239