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CP-25, a novel compound, protects against autoimmune arthritis by modulating immune mediators of inflammation and bone damage
Paeoniflorin-6′-O-benzene sulfonate (code: CP-25), a novel ester derivative of paeoniflorin (Pae), was evaluated in rats with adjuvant-induced arthritis (AA) to study its potential anti-arthritic activity. AA rats were treated with CP-25 (25, 50, or 100 mg/kg) from days 17 to 29 after immunization....
Autores principales: | Chang, Yan, Jia, Xiaoyi, Wei, Fang, Wang, Chun, Sun, Xiaojing, Xu, Shu, Yang, Xuezhi, Zhao, Yingjie, Chen, Jingyu, Wu, Huaxun, Zhang, Lingling, Wei, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869037/ https://www.ncbi.nlm.nih.gov/pubmed/27184722 http://dx.doi.org/10.1038/srep26239 |
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